• LabSMC, led by Dr. Yiliu Liu, is a dynamic research group dedicated to supramolecular polymer chemistry. Established in August 2018, our laboratory is affiliated with the School of Emergent Soft Matter at the South China University of Technology. Our research seamlessly integrates synthetic polymer chemistry with controllable molecular assembly. On one hand, inspired by living systems in nature, we develop innovative strategies for controlled polymer synthesis and macromolecular assembly, enabling the creation of biomimetic functional systems and materials. On the other hand, we leverage principles from supramolecular chemistry, macromolecular chemistry, and synthetic biology to engineer living biological systems with the goal of developing biohybrid and bioactive materials. We warmly welcome students and postdoctoral researchers with an interest in molecular assembly, precision polymer synthesis, biomimetic and biohybrid materials, and related fields to join our team!

  • Our Research Topics

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    TOPIC I :

    Molecular Motif

    Exploring the Macromolecular and Supramolecular Chemistry of Cyclopropeniums

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    TOPIC II :

    Multiscale Synthesis

    Constructing Bioinspired Supramolecular Systems by Covalent-Noncovalent Synergestic Synthesis

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    TOPIC III :

    Materials / Technology

    Interfacing Living Biological Systems with Supramolecular Polymer Chemistry and Catalysis

  • Selected Recent Publications

    The full publication list is available on Google Scholar / LabSMC (CHN)

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    Nano-construction on Living Cell Surfaces with Cucurbit[7]uril-based Supramolecular Polymer Chemistry: Towards Cell-based Delivery of Bio-orthogonal Catalytic Systems

    J. Am. Chem. Soc. 2023, 145, 26983-26992.

    F. Huang; J. Liu; Y. Liu* et al.

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    In Situ Supramolecular Polymerization via Organometallic-Catalyzed Macromolecular Metamorphosis

    CCS Chem. 2023, 5, 761-771.

    X. Yang; Y. Liu* et al.

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    Exploring the Supramolecular Chemistry of Cyclopropeniums : Halogen Bonding Induced Electrostatic Assembly of Polymers

    Chem. Sci. 2023, 14, 9820-9826.

    S. Huang; Y. Liu* et al.

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    Engineering Living Cells with Cucurbit[7]uril-based Supramolecular Polymer Chemistry: from Cell Surface Engineering to Manipulation of Subcellular Organelles

    Chem. Sci. 2022, 13, 8885-8894.

    F. Huang; Y. Liu* et al.

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    Promoting Halogen-Bonding Catalyzed Living Radical Polymerization through Ion-Pair Strain

    Chem. Sci. 2022, 13, 11352-11359.

    S. Huang; Y. Liu* et al.

  • Current Group Members

    The LabSMC Alumni List is available on our Chinese Version Website

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    Prof. Dr. Yiliu Liu

    Principal Investigator

    From 2018.08 -

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    Dr. Fang Huang

    Postdoctoral Researcher

    From 2024.08-

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    Cunluo Wu

    Ph.D. Student

    From 2021.09-

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    Qingqing Han

    Ph.D. student

    From 2022.09 -

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    Yunan Qin

    Ph.D. student

    From 2023.09 -

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    Yandan Zhang

    Research assistant

    From 2024.07 -

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    Bingfa Wu

    Master student

    From 2022.09 -

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    Peijun Lu

    Master student

    From 2022.09 -

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    Yuying Chen

    Master student

    From 2023.09 -

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    Qiuyuan Wu

    Master student

    From 2023.09 -

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    Haoxuan Li

    Master student

    From 2024.09 -

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    Tingxuan Chen

    Master student

    From 2024.09 -

  • Group Activities

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    Meijer Family Reunion at Westlake University

    2024.12.19

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    12th Singapore International Chemistry Conference

    2024.12.09

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    Tang Ao-Qing Foundation 15th Anniversary Ceremony

    2024.11.18